Top Campaigns by the Biggest Crypto Influencers on Twitter in 2025

Biggest crypto influencers Twitter campaign in action

In 2025, Twitter remains a powerhouse platform for crypto discussions, trends, and influencer-driven campaigns. The biggest crypto influencers on Twitter have not only shaped blockchain conversations but also driven impactful marketing campaigns for blockchain projects, NFTs, DeFi platforms, and Web3 technologies.

This article highlights the most successful campaigns led by the biggest crypto influencers on Twitter in 2025, showcasing how their reach and expertise translated into measurable results. If you’re a brand looking to tap into the power of Twitter influencers, Flexe.io offers tailored solutions to connect you with the best voices in the industry. Reach out to us via Telegram to discuss your campaign needs.


Why Twitter Campaigns Are Critical for Crypto Marketing

The fast-paced nature of Twitter makes it ideal for running real-time campaigns that engage audiences and create viral buzz. Crypto influencers use threads, live discussions, and collaborations to promote projects effectively. Their campaigns often result in:

  • Increased Brand Awareness
  • Higher Community Engagement
  • Boosted Token Sales or Project Participation

By collaborating with these influencers, brands can amplify their message to a highly targeted and engaged audience.


Top Campaigns by the Biggest Crypto Influencers on Twitter in 2025

1. Vitalik Buterin (@VitalikButerin): Ethereum Layer 2 Adoption Campaign

Vitalik used his massive influence to promote Ethereum’s Layer 2 scaling solutions, emphasizing reduced gas fees and enhanced transaction speeds. His educational threads about the benefits of Layer 2 solutions sparked widespread adoption and integration among dApps and DeFi platforms.


2. Changpeng Zhao (CZ) (@cz_binance): Binance Academy Expansion

CZ launched a campaign highlighting Binance Academy’s educational resources for blockchain enthusiasts. His tweets included tips for beginners, creating massive engagement and encouraging new users to explore Binance’s ecosystem.


3. Michael Saylor (@saylor): Bitcoin as Digital Gold

Saylor continued his crusade for institutional Bitcoin adoption by promoting a series of threads on Bitcoin’s resilience and its role as a hedge against inflation. His campaign inspired renewed interest among corporate investors.


4. Laura Shin (@laurashin): Unchained Podcast NFT Launch

Laura leveraged her influence to promote exclusive NFTs tied to her Unchained podcast episodes. Her campaign focused on creating value for her community, merging the worlds of content creation and blockchain.


5. Anthony Pompliano (Pomp) (@APompliano): Bitcoin Education Drive

Influential crypto figure leading a blockchain discussion

Pomp launched a campaign targeting students and young professionals, promoting Bitcoin as a revolutionary technology. His bite-sized, data-driven tweets gained significant traction, sparking discussions on crypto adoption among the younger generation.


6. Cobie (@cobie): DeFi Meme Awareness Campaign

Cobie creatively used memes and humor to promote a new DeFi project. His relatable content combined with actionable insights generated massive engagement, successfully onboarding thousands of new users to the platform.


7. Andreas M. Antonopoulos (@aantonop): Crypto Security Campaign

Andreas ran an awareness campaign about the importance of wallet security and self-custody. His detailed threads and live Q&A sessions educated the community, reducing cases of wallet hacks and scams.


8. Willy Woo (@woonomic): Bitcoin Market Insights Campaign

Willy Woo’s on-chain analytics campaign focused on showcasing Bitcoin’s market health and growth potential. His data-driven tweets boosted confidence among traders and long-term investors.


9. Meltem Demirors (@Melt_Dem): Women in Crypto Initiative

Meltem led a campaign to encourage more women to join the crypto space, sharing stories of successful female leaders in blockchain and offering mentorship opportunities through Twitter discussions.


10. Chris Dixon (@cdixon): Web3 Creator Economy Campaign

Chris promoted a campaign showcasing how Web3 empowers creators by eliminating intermediaries. His tweets highlighted success stories, sparking discussions and drawing creators into the decentralized economy.


How Brands Can Create Successful Campaigns with Twitter Influencers

  1. Target the Right Audience: Collaborate with influencers whose followers align with your brand’s goals.
  2. Leverage Engagement Tools: Use threads, polls, and live discussions to maximize interaction.
  3. Work with Professionals: Agencies like Flexe.io specialize in connecting brands with the right influencers and managing campaigns for optimal results.

Why Choose Flexe.io for Influencer Marketing on Twitter?

At Flexe.io, we craft customized influencer marketing strategies that deliver results. With a vast network of crypto influencers, including Twitter’s most prominent voices, we help brands build impactful campaigns.

Explore our influencer marketing services or contact us on Telegram to kickstart your marketing efforts.


Conclusion

Successful Twitter crypto influencer campaign in 2025

The biggest crypto influencers on Twitter in 2025 have transformed how projects connect with audiences, leveraging their reach to create impactful campaigns. By partnering with these influencers, brands can amplify their message, drive engagement, and achieve tangible results.

If you’re ready to elevate your crypto project, trust Flexe.io to connect you with the most influential voices in the industry and manage campaigns that deliver measurable success.

Time to boost your project